SNPMiner Trials by Shray Alag


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Report for SNP rs12654788

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

There is one clinical trial.

Clinical Trials


1 LA PREDISPOSIZIONE AL DOLORE PERSISTENTE POST OPERATORIO IN AMBITO ORTOPEDICO: ASPETTI GENETICI

The study purpose is to examine polymorphism of genes associated to post-operative persistent pain and to verify the possible association between genotype phenotype and ADRB2 polymorphism in orthopaedic surgery. The primary aim is to evaluate the expression of ADBR2 in VAS>4 patients and to compare it to those with VAS<4.

NCT01989351 Chronic Pain
MeSH: Chronic Pain
HPO: Chronic pain

Frequency of SNPs rs12654788 and rs1042713 of ADBR2 gene in patients who complain persistent pain 4 months postoperatively compared to chronic pain free patients.. null.

Primary Outcomes

Measure: Frequency of SNPs rs12654788 and rs1042713 of ADBR2 gene in patients who complain persistent pain 4 months postoperatively compared to chronic pain free patients.

Time: 4 months after surgery

Secondary Outcomes

Measure: Expression frequency of OPRM1, COMT, IL1Ra

Time: 6, 12, 24, 48 hours

Measure: Serum concentration of TNFα, TGFβ, IFNγ, IL-6 and IL-10 obtained with ELISA system

Time: 6, 12, 24 and 48 hours postoperatively


HPO Nodes


Chronic pain
Genes 3
ATXN3 TGFB2 FLVCR1