SNPMiner Trials (Home Page)
Report for SNP rs12654788
Developed by Shray Alag, 2020.
SNP Clinical Trial Gene
There is one clinical trial.
Clinical Trials
1 LA PREDISPOSIZIONE AL DOLORE PERSISTENTE POST OPERATORIO IN AMBITO ORTOPEDICO: ASPETTI GENETICI
The study purpose is to examine polymorphism of genes associated to post-operative persistent pain and to verify the possible association between genotype phenotype and ADRB2 polymorphism in orthopaedic surgery. The primary aim is to evaluate the expression of ADBR2 in VAS>4 patients and to compare it to those with VAS<4.
NCT01989351 Chronic Pain MeSH: Chronic Pain
HPO: Chronic pain
Frequency of SNPs rs12654788 and rs1042713 of ADBR2 gene in patients who complain persistent pain 4 months postoperatively compared to chronic pain free patients.. null.
Primary Outcomes
Measure: Frequency of SNPs rs12654788 and rs1042713 of ADBR2 gene in patients who complain persistent pain 4 months postoperatively compared to chronic pain free patients. Time: 4 months after surgerySecondary Outcomes
Measure: Expression frequency of OPRM1, COMT, IL1Ra Time: 6, 12, 24, 48 hoursMeasure: Serum concentration of TNFα, TGFβ, IFNγ, IL-6 and IL-10 obtained with ELISA system Time: 6, 12, 24 and 48 hours postoperatively