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Report for SNP rs4950928

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

There is one clinical trial.

Clinical Trials


1 The Relationship Between Single Nucleotide Polymorphisms of Chitinase 3-like 1 Gene,YKL-40 Serum Levels and Adult Asthma

The objective of this study was to investigate the relationship between single nucleotide polymorphism of chitinase 3-like 1 and human asthma.

NCT01348932 Asthma
MeSH: Asthma
HPO: Asthma

The C-allele of the -131 C→G (rs4950928) polymorphism of CHI3L1 has been shown to associate with bronchial hyperresponsiveness and reduced lung function.

In contrast to preliminary studies, the investigators predict the rs4950928 G allele, and not the C allele, was found to be associated with asthma.



HPO Nodes


Asthma
Genes 138
DNAH9 COL5A2 DNAH11 NFKB2 TDGF1 DDX41 SPAG1 ARMC4 GP1BA GAS2L2 CCDC151 ERCC2 TNF SPINK5 GP1BB GAS1 TGIF1 CCL11 CDON DLL1 CFAP221 PTGER2 TBX21 LRBA RSPH4A CFTR FLG NME8 DNAAF4 ZIC2 SCGB3A2 CCDC65 SDHD ADRB2 TBX1 GP1BB SIX3 IDS NODAL NSUN2 ELOVL4 PEPD CARMIL2 CFAP300 FGF8 GP9 FOXJ1 DNAI1 CASP8 DOCK8 CCDC151 DISP1 IL13 CCNO ALMS1 RSPH1 CCDC39 STK36 MUC7 NOD2 CARD11 CCDC28B DNAL1 DNAH1 ZMYND10 RSPH3 RSPH9 MS4A2 PLA2G7 HNMT DRC1 NKX2-1 SHH COL1A1 CCDC103 SPINK5 FGFR1 DNAAF3 MTOR HIRA LRRC56 LRRC6 GAS8 CFAP298 NEK9 CCDC40 IL4R PGM3 DOCK8 DNAAF2 GLI2 RREB1 TGFB1 PTCH1 GRHL2 SIK3 SCN4A BBS1 TALDO1 DNAAF1 NKX2-1 OFD1 TRAIP PLCG2 HLA-G COL5A1 ALMS1 DNAI2 BCL11B LIG4 GTF2H5 PGM3 ARVCF PEX5 CDSN SEC24C DNAAF6 DNAH5 CCDC114 ADA PLA2G7 JMJD1C DNAJB13 RPGR FOXH1 ALOX5 TTC25 FCGR2A TBX1 COMT COX4I2 UFD1 SPEF2 SUFU DNAAF5 LIFR MCIDAS HYDIN