SNPMiner Trials by Shray Alag


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Report for SNP rs2227902

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

There is one clinical trial.

Clinical Trials


1 Effect of REST on Cognitive Function and Hippocampus in the Alzheimer Disease Continuum

The investigators assume that REST gene polymorphism affects REST protein concentration, and REST protein concentration in peripheral blood is related to cognitive function and hippocampus. In this current study, REST protein content and gene polymorphism will be obtained in peripheral blood in AD and normal control. The effect of REST gene polymorphism on REST protein concentration will be discovered.The relationship between REST protein concentration and cognitive function will be found, as well as the relationship between REST protein concentration and hippocampus.

NCT03884023 Alzheimer's Disease
MeSH: Alzheimer Disease
HPO: Alzheimer disease

Rate of Gene polymorphism in rs2227902 and rs3796529.. Verifying the value of REST gene polymorphism as an early markers of Alzheimer's Disease.

Primary Outcomes

Description: Verifying the value of REST gene polymorphism as an early markers of Alzheimer's Disease

Measure: Rate of Gene polymorphism in rs2227902 and rs3796529.

Time: baseline

Description: Verifying the value of REST protein detection as an early markers of Alzheimer's Disease

Measure: Concentration of REST protein

Time: baseline


HPO Nodes


Alzheimer disease
Genes 13
MPO HFE ABCA7 PSEN1 APOE APP A2M CACNA1G PSEN2 APOE PLAU GATA1 NOS3