SNPMiner Trials by Shray Alag


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Report for SNP rs20432111

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

There is one clinical trial.

Clinical Trials


1 Quantification of NLRP3 (rs4612666) and CARD8 Gene (rs2043211) in Subgingival Plaque and Blood Samples of Generalized Chronic Periodontitis Subjects With and Without Coronary Heart Disease

Quantification of NLRP3 (rs4612666) and CARD8 (rs20432111) will be analysed in the subgingival plaque and blood samples of generalized chronic periodontitis with and without coronary heart disease. The demographic and the periodontal parameters were assessed and correlated with the quantification of NLRP3 (rs4612666) and CARD8 (rs2043211) was analysed with RT-PCR

NCT04127487 Pe Periodontal Diseases Coronary Artery Disease
MeSH: Periodontitis Chronic Periodontitis Periodontal Diseases Coronary Artery Disease
HPO: Coronary artery atherosclerosis Periodontitis

Quantification of NLRP3 (rs4612666) and CARD8 Gene (rs2043211) in Generalized Chronic Periodontitis Subjects Quantification of NLRP3 (rs4612666) and CARD8 (rs20432111) will be analysed in the subgingival plaque and blood samples of generalized chronic periodontitis with and without coronary heart disease.

The demographic and the periodontal parameters were assessed and correlated with the quantification of NLRP3 (rs4612666) and CARD8 (rs2043211) was analysed with RT-PCR Expression of NLRP3 (rs4612666) and CARD8 (rs20432111) gene.

Expression of NLRP3 (rs4612666) and CARD8 (rs20432111) gene using RT-PCR.

Quantification of NLRP3 (rs4612666) and CARD8 (rs20432111) gene.

Quantification of NLRP3 (rs4612666) and CARD8 (rs20432111) gene using RT-PCR.

Primary Outcomes

Description: Expression of NLRP3 (rs4612666) and CARD8 (rs20432111) gene using RT-PCR

Measure: Expression of NLRP3 (rs4612666) and CARD8 (rs20432111) gene

Time: 12 months

Secondary Outcomes

Description: Quantification of NLRP3 (rs4612666) and CARD8 (rs20432111) gene using RT-PCR

Measure: Quantification of NLRP3 (rs4612666) and CARD8 (rs20432111) gene

Time: 12 months


HPO Nodes


Periodontitis
Genes 41
PLG GORAB PLG DKC1 FGF3 CTSC CTSC AP3B1 SLC35C1 ELANE NOTCH2 CTSC PLG RTEL1 CXCR4 TERC PARN GFI1 TCIRG1 FERMT1 OCRL ELANE C1S SRP54 ITGB2 C1R USB1 CTC1 LYST NOP10 COL3A1 NPM1 WRAP53 C1S TERT COL3A1 C1R NHP2 CTSC TINF2 FERMT1
Coronary artery atherosclerosis
Genes 48
LMNA LDLRAP1 LDLR ACTA2 CYP7A1 FBN1 APOE APOB ESR1 MAT2A ABCA1 KCNJ5 ABCG8 MYH11 ZNF687 TGFB2 LMNA LMNA ELN LMNA LIPC PPARG LMNA FOXE3 SERPIND1 SMAD4 TGFBR2 SMPD1 MFAP5 ABCA1 APOB LMNA LOX SMAD3 MYH11 MYH11 LOX LMNA PCSK9 ACTA2 ABCG8 ZMPSTE24 TGFB3 PRKG1 TGFBR1 MYLK CEP19 ABCG5