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Report for Clinical Trial NCT01107158

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

The Role of Two Nuclear Receptors for Oxysterols as a Molecular Cause of Uterine Dystocia: LXR Alpha and LXR Beta

Despite the fact that a link between cholesterol and the myometrium has been clearly established, no study investigating aspects of cholesterol metabolism and uterine dystocia currently exists. This study is a pilot study whose aim is to test the hypothesis that an association between uterine dystocia and single-nucleotide polymorphisms (SNPs) in the genes coding for the LXRs.

NCT01107158 Uterine Inertia Dystocia
MeSH: Dystocia Uterine Inertia

1 Interventions

Name: Whole blood sampling

Description: Whole blood sampling for SNP polymorphism analysis

Type: Biological

Group 1 Group 2


Primary Outcomes

Description: The polymorphisms of interest are the following SNPs: rs3758673, rs3758674, rs12221497, rs11039155, rs2279238, rs7120118, rs35463555, rs1052533, rs2248949, rs41432149, rs1405655, rs4802703.

Measure: The multi-loci genotype of the target DNA sequence.

Time: Day 1

Time Perspective: Cross-Sectional

Case Control


There are 12 SNPs

SNPs


1 rs1052533

The polymorphisms of interest are the following SNPs: rs3758673, rs3758674, rs12221497, rs11039155, rs2279238, rs7120118, rs35463555, rs1052533, rs2248949, rs41432149, rs1405655, rs4802703.. Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Uterine Inertia Dystocia Dystocia Uterine Inertia null


2 rs11039155

The polymorphisms of interest are the following SNPs: rs3758673, rs3758674, rs12221497, rs11039155, rs2279238, rs7120118, rs35463555, rs1052533, rs2248949, rs41432149, rs1405655, rs4802703.. Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Uterine Inertia Dystocia Dystocia Uterine Inertia null


3 rs12221497

The polymorphisms of interest are the following SNPs: rs3758673, rs3758674, rs12221497, rs11039155, rs2279238, rs7120118, rs35463555, rs1052533, rs2248949, rs41432149, rs1405655, rs4802703.. Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Uterine Inertia Dystocia Dystocia Uterine Inertia null


4 rs1405655

The polymorphisms of interest are the following SNPs: rs3758673, rs3758674, rs12221497, rs11039155, rs2279238, rs7120118, rs35463555, rs1052533, rs2248949, rs41432149, rs1405655, rs4802703.. Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Uterine Inertia Dystocia Dystocia Uterine Inertia null


5 rs2248949

The polymorphisms of interest are the following SNPs: rs3758673, rs3758674, rs12221497, rs11039155, rs2279238, rs7120118, rs35463555, rs1052533, rs2248949, rs41432149, rs1405655, rs4802703.. Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Uterine Inertia Dystocia Dystocia Uterine Inertia null


6 rs2279238

The polymorphisms of interest are the following SNPs: rs3758673, rs3758674, rs12221497, rs11039155, rs2279238, rs7120118, rs35463555, rs1052533, rs2248949, rs41432149, rs1405655, rs4802703.. Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Uterine Inertia Dystocia Dystocia Uterine Inertia null


7 rs35463555

The polymorphisms of interest are the following SNPs: rs3758673, rs3758674, rs12221497, rs11039155, rs2279238, rs7120118, rs35463555, rs1052533, rs2248949, rs41432149, rs1405655, rs4802703.. Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Uterine Inertia Dystocia Dystocia Uterine Inertia null


8 rs3758673

The polymorphisms of interest are the following SNPs: rs3758673, rs3758674, rs12221497, rs11039155, rs2279238, rs7120118, rs35463555, rs1052533, rs2248949, rs41432149, rs1405655, rs4802703.. Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Uterine Inertia Dystocia Dystocia Uterine Inertia null


9 rs3758674

The polymorphisms of interest are the following SNPs: rs3758673, rs3758674, rs12221497, rs11039155, rs2279238, rs7120118, rs35463555, rs1052533, rs2248949, rs41432149, rs1405655, rs4802703.. Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Uterine Inertia Dystocia Dystocia Uterine Inertia null


10 rs41432149

The polymorphisms of interest are the following SNPs: rs3758673, rs3758674, rs12221497, rs11039155, rs2279238, rs7120118, rs35463555, rs1052533, rs2248949, rs41432149, rs1405655, rs4802703.. Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Uterine Inertia Dystocia Dystocia Uterine Inertia null


11 rs4802703

The polymorphisms of interest are the following SNPs: rs3758673, rs3758674, rs12221497, rs11039155, rs2279238, rs7120118, rs35463555, rs1052533, rs2248949, rs41432149, rs1405655, rs4802703.. Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Uterine Inertia Dystocia Dystocia Uterine Inertia null


12 rs7120118

The polymorphisms of interest are the following SNPs: rs3758673, rs3758674, rs12221497, rs11039155, rs2279238, rs7120118, rs35463555, rs1052533, rs2248949, rs41432149, rs1405655, rs4802703.. Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Inclusion Criteria: - Patients undergoing C-section for a dystocia: 2 to 3 hours of stagnation in labor progress are observed (ie no increasing dilation, and uterine contractions less that 3-5 per 10 minutes) in spite of measures taken to overcome dystocia (oxytocin injection and artificial breaking of waters) - the child is alive - the child does not have apriori known malformations that could interfere with a vaginal birth - foetus in cephalic position - full term pregnancy (>= 37 weeks of amenorrhea) - single birth - patient has signed consent - patient is affiliated with a social security system Exclusion Criteria: - vaginal birth - programmed C-section - C-section is chosen because the fetus has a cardia rhythm problem, and there is no stagnation in the labor process - multiple pregnancy - the child is in a breech position - premature birth (<37 weeks amenorrhea) - in utero fetal death - fetal malformation known before birth that could interfere with a vaginal birth - non french-speaking patient (impossible to correctly inform the patient) - patient under guardianship Uterine Inertia Dystocia Dystocia Uterine Inertia null



HPO Nodes