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Report for Clinical Trial NCT02720861

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

Prevalence of Genetic Polymporphism on RNF213 rs112735431 Gene in Non-cardioemboli Ischemic Cerebrovascular Disease: A Cross-sectional Study in Thai Patients

To explore the prevalence of genetic polymorphism on RNF213 rs112735431 gene in non-cardioembolic ischemic cerebrovascular disease in Thai patients.

NCT02720861 Ischemic Stroke
MeSH: Cerebrovascular Disorders Ischemia

1 Interventions

Name: DNA sequencing

Description: withdraw 3m blood from vein only once during the whole design to analyse on DNA sequencing on RNF213 rs112735431 Gene

Type: Genetic

non embolic ischemic stroke


Primary Outcomes

Measure: Number of Participants With RNF213 rs112735431 Gene polymorphism

Time: 1 year

Time Perspective: Cross-Sectional

Cohort


There is one SNP

SNPs


1 rs112735431

Prevalence of Genetic Polymporphism on RNF213 rs112735431 Gene in Non-cardioemboli Ischemic Cerebrovascular Disease: A Cross-sectional Study in Thai Patients.

Prevalence of Genetic Polymporphism on RNF213 rs112735431 Gene in Non-cardioemboli Ischemic Cerebrovascular Disease To explore the prevalence of genetic polymorphism on RNF213 rs112735431 gene in non-cardioembolic ischemic cerebrovascular disease in Thai patients.

Number of Participants With RNF213 rs112735431 Gene polymorphism.

Inclusion Criteria: - Nationality in Thailand - Age equal or more than 18 years - Clinical and imaging diagnosis of acute ischemic stroke - Patient consent to participate in the research Exclusion Criteria: - High risk for cardioembolic stroke by TOAST classification - Contraindication for venipuncture - Pregnancy or breast feeding patient - History of head and neck radiation - Down's syndrome - Marfan syndrome - Autoimmune disease such as SLE - Ongoing malignancy or remission of malignancy less than 1year Inclusion Criteria: - Nationality in Thailand - Age equal or more than 18 years - Clinical and imaging diagnosis of acute ischemic stroke - Patient consent to participate in the research Exclusion Criteria: - High risk for cardioembolic stroke by TOAST classification - Contraindication for venipuncture - Pregnancy or breast feeding patient - History of head and neck radiation - Down's syndrome - Marfan syndrome - Autoimmune disease such as SLE - Ongoing malignancy or remission of malignancy less than 1year Ischemic Stroke Cerebrovascular Disorders Ischemia This is an cross-sectional observational study in Chulalongkorn hospital, to determine the prevalence of genetic polymorphism on RNF213 rs112735431 gene in non-cardioembolic ischemic cerebrovascular disease.



HPO Nodes