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Report for Clinical Trial NCT03907722

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

The 3q25 rs2305619 Polymorphism is Associated With Coronary Microvascular Obstruction Following Primary Angioplasty for Acute ST-segment Elevation Myocardial Infarction

The investigators enrolled 217 patients with acute STEMI undergoing primary PCI. The rs2305619 polymorphism was evaluated by real time PCR and plasma PTX3 concentration was assessed by human PTX3 ELISA kit.

NCT03907722 STEMI Microvascular Coronary Artery Disease
MeSH: Coronary Artery Disease
HPO: Coronary artery atherosclerosis

1 Interventions

Name: Long pentraxin 3

Description: Primary PCI

Type: Other

Genotypic variants


Primary Outcomes

Description: Percentage

Measure: Incidence of microvascular obstruction

Time: Immediate after pci

Secondary Outcomes

Description: Percentage

Measure: Incidence of mortality

Time: 30 days

Time Perspective: Cross-Sectional

Other


There is one SNP

SNPs


1 rs2305619

The 3q25 rs2305619 Polymorphism is Associated With Coronary Microvascular Obstruction Following Primary Angioplasty for Acute ST-segment Elevation Myocardial Infarction.

The 3q25 rs2305619 Polymorphism Associates With Microvascular Obstruction in STEMI The investigators enrolled 217 patients with acute STEMI undergoing primary PCI.

The rs2305619 polymorphism was evaluated by real time PCR and plasma PTX3 concentration was assessed by human PTX3 ELISA kit.

The rs2305619 polymorphism was evaluated by real time PCR and plasma PTX3 concentration was assessed by human PTX3 ELISA kit.



HPO Nodes


HPO:
Coronary artery atherosclerosis
Genes 48
LMNA LDLRAP1 LDLR ACTA2 CYP7A1 FBN1 APOE APOB ESR1 MAT2A ABCA1 KCNJ5 ABCG8 MYH11 ZNF687 TGFB2 LMNA LMNA ELN LMNA LIPC PPARG LMNA FOXE3 SERPIND1 SMAD4 TGFBR2 SMPD1 MFAP5 ABCA1 APOB LMNA LOX SMAD3 MYH11 MYH11 LOX LMNA PCSK9 ACTA2 ABCG8 ZMPSTE24 TGFB3 PRKG1 TGFBR1 MYLK CEP19 ABCG5